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ETF Profiles

MSOS ETF: What Is It? A Complete Guide to Returns, Fees, Holdings and Alternative ETFs

Updated May 9, 2026

An actively managed ETF focused on U.S. domestic companies, it concentrates on key players in U.S. cannabis production and distribution, aiming to benefit from policy changes and market expansion.

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🏷️

What Is This ETF?

The fund invests in large multi-state operators (Multi-State Operators) that run businesses across several U.S. states. It is actively managed to respond sensitively to changes in the federal regulatory environment, and it uses derivative contracts and similar instruments to gain exposure to quality companies that are difficult to access through direct listings.

It is suited to aggressive investors who expect further cannabis legalization in the U.S. and explosive industry growth, and who can tolerate high volatility.

It is an actively managed ETF launched in 2020 by AdvisorShares.

💰

How Does It Invest?

ItemDetails
Main assetsU.S. cannabis and hemp-related companies
Management styleActive (specialized in the U.S. market)
Rebalancing frequencyAs needed
Dividend frequencyAnnual
Expense ratio0.78%

The fund concentrates its investments in a carefully selected group of leading operators in the U.S. cannabis industry. Because federal regulation and other factors keep some of these companies off major exchanges, the fund uses derivatives to track their performance, and the manager flexibly adjusts weightings in line with regulatory changes and earnings trends.

  • A differentiated portfolio made up solely of U.S. domestic cannabis companies
  • An active management strategy that responds to changes in the regulatory environment
📐

Size and Costs

Assets under management (AUM) stand at $755.9M, and the expense ratio (Expense Ratio) is 0.78% per year.

PAVE and IFRA shown in the table are infrastructure-related ETFs, and UFO is a thematic product investing in the space industry, so they belong to different sectors from MSOS. However, they may share some common ground as innovation themes.

📈

Performance and Trends

1-Year Price Performance
Dividend & Yield
1Y Return -8.4%
Next Ex-Dividend Date 12/23/2021
52-Week Price Range
$4
Low $3 High $7
vs. low +33.11% vs. high -45.66%

Share price volatility has been very large, driven by moves toward looser federal regulation and results in earnings season, and the fund has at times staged strong rebounds as policy uncertainty eased.

Money seeking alternative investments coexists with short-term speculative capital betting on policy change, and inflows tend to surge sharply on news such as the passage of related legislation.

⚔️

Pros and Cons

The fund offers high return potential from industry growth, but policy risk and high price volatility are key factors to weigh carefully.

💪 Key Strengths

Focus on the U.S. market
Unlike other ETFs weighted toward Canadian companies, it invests only in U.S. domestic companies, where the actual market is much larger.
Benefits from industry growth
It captures direct revenue growth from the expanding legalization of medical and recreational cannabis.
Active response
In a complex regulatory environment, professional managers select promising stocks and manage risk.

⚠️ Points to Watch

Policy and regulatory risk
Delays in federal legalization or tighter regulation could significantly damage corporate value.
High volatility
Given the early growth stage of the industry, share prices swing far more with market sentiment than in typical sectors.
Listing restriction risk
Most portfolio companies trade on the OTC market, so liquidity and access to information may be limited.
🔄

Alternative ETFs and Related Products

Within the cannabis sector, investors can also consider MJ, CNBS and YOLO, which have a higher weighting in Canadian companies and offer global diversification unlike MSOS. For those widening their view to related supply and consumables companies, GRWG is also worth considering.

Peer Comparison ETFs
TickerNamePriceChangeAUMTotal Expense RatioDividend Yield1Y
PAVEPAVEGlobal X U.S. Infrastructure Development ETF$53.52-1.8%$14.1B0.47%0.81%+11.4%
IFRAIFRAiShares U.S. Infrastructure ETF$58.30-0.4%$4.1B0.30%1.74%+10.7%
UFOUFOProcure Space ETF$40.24-3.5%$469.8M0.75%0.38%+8.1%
FAIFAIFirst Trust Bloomberg Artificial Intelligence ETF$51.16-4.8%$257.8M0.65%-+18.9%
AIFDAIFDTCW Artificial Intelligence ETF$47.25-5.8%$128.3M0.75%-+24.0%
Top Holdings
TickerNameWeightPriceChangeMarket CapP/EDividend Yield
TRLVTRLVTrulieve Cannabis Corp0.10%$10.28-3.0%$2.0B--
VFFVFFVillage Farms International Inc0.02%$2.50-3.5%$305.7M13.4-
MSDLMSDLMorgan Stanley Direct Lending Fund0.03%$13.87-0.6%$1.2B20.113.04%
GLASGLASGlass House Brands Inc0.01%$2.18-4.4%$168.8M--
SNDLSNDLSNDL Inc0.00%$1.24-4.6%$303.5M--
✅

Investor Checkpoints

MSOS is a specialized thematic product that concentrates on the U.S. cannabis industry, so before deciding to invest, please check the regulatory situation and volatility closely using the key checklist below.

CheckpointWhat to CheckCurrent Status
⚖️ Passage of legislationCheck federal legalization and financial services access billsOngoing monitoring
💸 Fee levelWhether you are aware of the high operating costs from derivative useNeeds review
📈 Price volatilityAssess your tolerance for sharp short-term price swingsVery high
🏢 Corporate fundamentalsTrends in the major operators' return to profitability and financial healthImproving

This is a high-risk product whose asset value can change sharply depending on political decisions. From a diversification standpoint, allocating only a very small portion of your portfolio is recommended.

It is one clear option for those who want to invest in the distinctive growth potential of the U.S. cannabis market. It is a useful tool for aggressive investors who are counting on regulatory easing as a momentum driver.

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Disclaimer: This content is for informational purposes only and does not constitute investment advice. All investment responsibility lies with the investor.

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