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What Is the XLVI ETF? Returns, Expense Ratio, Holdings and Alternative ETFs Explained

Updated August 17, 2026 · First published August 17, 2026

The State Street Health Care Select Sector SPDR Premium Income ETF, or XLVI ETF, combines health care sector exposure with option premium income. It is important to weigh its dividend-like distribution flow, the cap on upside participation from its call option strategy, and sector concentration risk together.

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What Is the State Street Health Care Select Sector SPDR Premium Income ETF?

The XLVI ETF holds an underlying ETF tied to the health care sector and sells call options on that underlying ETF to pursue premium income. As a result, performance can be affected not only by the direction of health care stocks but also by option market volatility and strike conditions.

It suits investors who want to keep health care sector exposure while also seeking a source of distributions, and who understand that participation in strong rallies may be limited.

It is an actively managed ETF run by State Street.

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How Does the State Street Health Care Select Sector SPDR Premium Income ETF Invest?

ItemDetails
Tracked IndexNot applicable (actively managed)
Management StyleActive management with call option selling
Rebalancing FrequencyAdjusted at the manager's discretion
Distribution FrequencyDistribution history exists (frequency is irregular; do not assume a fixed schedule)
Expense Ratio0.35%

This product invests in a health care sector underlying ETF while selling call options to earn premiums. It reflects both the price movements of the underlying asset and the option premium environment. Selling call options pursues a steady source of income, but it can reduce participation during sharp rallies.

  • Combines health care sector exposure with option income
  • Holds the underlying ETF while selling call options
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Size and Costs of the State Street Health Care Select Sector SPDR Premium Income ETF (AUM and Management Fee)

Assets under management (AUM) stand at $32.9M, and the Expense Ratio is 0.35% per year.

Trading liquidity and bid-ask spreads for the XLVI ETF can vary with market conditions, so it is advisable to check execution conditions when placing orders.

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Performance and Trends of the State Street Health Care Select Sector SPDR Premium Income ETF

1-Year Price Performance
Dividend & Yield
Dividend Yield 12.11%
Annual Dividend (TTM) $3.29
1Y Return +4.1%
Next Ex-Dividend Date 10/1/2026
52-Week Price Range
$27
Low $24 High $27
vs. low +12.15% vs. high -0.77%

The performance of the XLVI ETF is shaped by a combination of earnings expectations for health care companies, the regulatory environment, demand for defensive stocks, and option premium conditions. When the underlying ETF moves gently, the effect of premium income can stand out, but in strong rallies the terms of the call option contracts may limit participation in gains.

Demand for distribution-style cash flow can shift with volatility and the interest rate environment. Investors should also consider whether changes in fund flows could affect trading conditions and the gap between market price and net asset value. Policy, cost, and innovation developments surrounding the health care sector are also worth monitoring.

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Pros and Cons of the State Street Health Care Select Sector SPDR Premium Income ETF

Its distinguishing feature is the combination of health care sector exposure and option premium income, but investors must accept limited upside participation and sector concentration risk.

💪 Key Strengths

Use of Option Premiums
The structure pursues a source of distributions by selling call options on the underlying ETF.
Health Care Sector Exposure
It gives exposure to health care related industries such as pharmaceuticals and medical services.
Active Management
Managers can apply discretion based on option strike conditions and the market environment.

⚠️ Points to Watch

Limited Upside Participation
Selling call options can limit participation in gains when the underlying asset rises quickly.
Sector Concentration
Health care regulation, policy, and shifts in industry competition can affect the value of the product.
Option and Liquidity Risk
If option prices and trading conditions change, the expected income and the market price may diverge.
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Alternative ETFs and Related Products to the State Street Health Care Select Sector SPDR Premium Income ETF

In the automated comparison table, the NVDY ETF uses a single-stock option income strategy, the MSTY ETF uses an option income strategy centered on a different single stock, and the FEPI ETF uses an option income strategy based on a basket of innovative companies. The TSLY ETF and YMAX ETF also use option premiums, but the XLVI ETF differs in its underlying asset and source of risk because it combines health care sector exposure with call option selling. These products differ in fee burden, assets under management, and distribution characteristics, so product structure and trading conditions should be compared together.

Peer Comparison ETFs
TickerNamePriceChangeAUMTotal Expense RatioDividend Yield1Y
NVDYNVDYYieldMax NVDA Option Income Strategy ETF$11.55-0.5%$1.3B1.09%52.44%-26.0%
MSTYMSTYYieldMax MSTR Option Income Strategy ETF$14.49+0.1%$1.1B1.03%127.43%-74.9%
FEPIFEPIREX FANG & Innovation Equity Premium Income ETF$40.16-0.0%$701.4M0.65%25.14%-16.2%
TSLYTSLYYieldMax TSLA Option Income Strategy ETF$21.59-0.5%$649.0M1.07%76.28%-48.8%
AMDYAMDYYieldmax AMD Option Income Strategy ETF$41.60+1.6%$441.6M1.00%76.39%-12.4%
Top Holdings
TickerNameWeightPriceChangeMarket CapP/EDividend Yield
XLVXLVState Street Health Care Select Sector SPDR ETF2.01%$179.28-1.1%$0.0M-1.42%
MYMKMYMKState Street My2031 Municipal Bond ETF0.01%$24.57+0.1%$0.0M-2.62%
MSBTMSBTMorgan Stanley Bitcoin Trust-0.00%$23.27-0.3%$0.0M--
MSOLMSOLMorgan Stanley Solana Trust-0.02%$28.11+0.0%$0.0M-0.79%
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Investor Checkpoints for the State Street Health Care Select Sector SPDR Premium Income ETF

When evaluating the XLVI ETF, do not judge it by distribution level alone. Check the price changes of the underlying health care ETF together with the cap on upside participation from call option selling. Because the fund has a distribution history but an irregular frequency, it is better to review actual disclosures and trading conditions than to assume a regular cash flow.

CheckpointWhat to CheckCurrent Status
Distribution HistoryReview distribution history and potential variabilityDistribution history exists (frequency is irregular; do not assume a fixed schedule)
Option StructureCheck how call option selling affects returnsUpside participation may be limited
Sector ConcentrationReview health care policy and industry variablesChanges are possible
Trading ConditionsCheck bid-ask spreads and order execution environmentVaries with market conditions

Selling call options can provide premium income, but it can limit participation in gains when the underlying asset rises strongly. The health care sector can also be sensitive to regulatory changes, research and development results, pricing policy, and competitive dynamics. When market volatility rises, uncertainty over option prices and trading conditions may also increase.

The XLVI ETF is an actively managed product worth considering for investors who want to add an option premium income structure to health care sector exposure. However, investors should not read the distribution history alone as proof that income will continue, and are advised to also weigh the cap on upside participation from call option selling, sector concentration, and trading conditions.

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Disclaimer: This content is for informational purposes only and does not constitute investment advice. All investment responsibility lies with the investor.

This article reflects information as of August 17, 2026.

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