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ETF Profiles

What Is the PPH ETF? A Complete Guide to Returns, Expense Ratio, Holdings and Alternative ETFs

Updated May 11, 2026

It concentrates on 25 large global pharmaceutical companies. It is a flagship pharma sector ETF that combines dividend stability with defensive characteristics.

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What Is This ETF?

It tracks the MVIS US Listed Pharmaceutical 25 Index and holds 25 companies with high liquidity and market capitalization among the global pharmaceutical firms listed in the United States.

It suits investors who want exposure to the long-term growth in healthcare demand driven by population aging, and who prefer dividend income and low volatility.

It is a passively managed (index-tracking) ETF launched by VanEck in 2011.

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How Does It Invest?

ItemDetails
Tracked IndexMVIS US Listed Pharmaceutical 25 Index
Management StylePassive (index-tracking)
Rebalancing FrequencyQuarterly
Dividend FrequencyQuarterly
Total Expense Ratio0.36%

It selects large blue-chip companies that account for a significant share of the global pharmaceutical industry. It includes not only U.S. companies but also major foreign pharmaceutical firms listed in the U.S., tracking the performance of the global pharmaceutical market as a whole.

  • High concentration in 25 core pharmaceutical stocks
  • Includes a weighting in non-U.S. global big pharma
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Size and Costs

Assets under management (AUM) stand at $1.1B, and the expense ratio is 0.36% per year.

Unlike the tech ETFs shown in the table, such as CLOU and SNSR, which focus on specific themes, PPH concentrates on the pharmaceutical sector, which values traditional earnings and dividends, and aims for stable portfolio management.

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Performance and Trends

1-Year Price Performance
Dividend & Yield
Dividend Yield 1.79%
Annual Dividend (TTM) $2.14
1Y Return +29.2%
Next Ex-Dividend Date 10/1/2026
52-Week Price Range
$119
Low $91 High $118
vs. low +31.07% vs. high 1.1%

The pharmaceutical sector is a classic defensive stock group and tends to hold up relatively well when market uncertainty rises. Recently, enthusiasm for innovative new drugs such as obesity treatments has driven share price gains at major companies, energizing the sector as a whole.

Long-term capital seeking both expectations for healthcare innovation and stable dividend income continues to flow in, and demand for defensive assets strengthens when recession fears emerge.

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Strengths and Weaknesses

By concentrating on high-quality pharmaceutical companies, it pursues stability and growth at the same time, but it remains exposed to company-specific risks such as failed drug approvals.

💪 Key Strengths

Strong Market Position
It invests in global big pharma companies protected by patents and high barriers to entry.
Defensive Characteristics
Its low correlation with the economic cycle helps reduce portfolio volatility in falling markets.
Global Exposure
Investors can share in the performance of leading global pharmaceutical firms, including those in Europe, not just U.S. companies.

⚠️ Points to Watch

High Concentration
With only 25 holdings, it reacts sensitively to the earnings and news of its top positions.
Regulatory Risk
Changes in government healthcare regulation, such as drug price cut policies, directly affect profitability.
Patent Expiration
There is a constant risk of lower revenue when the patents of key drugs expire.
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Alternative ETFs and Related Products

While NXTG, mentioned in the table, invests in 5G technology, PPH focuses on pharmaceuticals, the tangible fruit of biotechnology. Within the pharmaceutical sector itself, alternatives include IHE, which centers on U.S. companies, and the equal-weighted XPH, and XLV, which covers healthcare broadly, is also worth considering.

Peer Comparison ETFs
TickerNamePriceChangeAUMTotal Expense RatioDividend Yield1Y
TRFKTRFKPacer Data and Digital Revolution ETF$84.80-7.6%$1.1B0.49%0.03%+16.8%
NXTGNXTGFirst Trust Indxx NextG ETF$145.12-3.0%$547.7M0.70%1.36%+32.3%
CLOUCLOUGlobal X Cloud Computing ETF$28.02-4.2%$413.4M0.68%-+18.4%
WQTMWQTMWisdomTree Quantum Computing Fund$26.33-6.0%$309.5M0.45%--11.9%
ECONECONColumbia Research Enhanced Emerging Economies ETF$32.31-2.6%$297.0M0.47%1.5%+16.0%
Top Holdings
TickerNameWeightPriceChangeMarket CapP/EDividend Yield
LLYLilly(Eli) & Co0.39%$1417.54+3.2%$1.33T46.60.48%
NVSNovartis AG ADR0.21%$160.79-0.2%$294.3B30.72.7%
MRKMerck & Co Inc0.20%$149.52+2.2%$368.9B152.72.28%
NVONovo Nordisk ADR0.10%$40.00+2.2%$133.8B9.84.36%
PFEPfizer Inc0.05%$30.52+1.9%$174.0B40.45.65%
SNYSanofi ADR0.05%$44.34+2.8%$105.7B22.85.4%
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Investor Checkpoints

PPH is an efficient vehicle for investing in the giant pharmaceutical industry, which generates stable cash flow. Before investing, review the market environment and the product's specific features carefully using the key checklist below.

CheckpointWhat to CheckCurrent Status
💵 Expense LevelCheck cost competitiveness versus other ETFs in the sectorTop tier
💊 Drug PipelineReview the drug development status of major holdingsGood
📈 Policy EnvironmentLegislative trends on drug pricing in the U.S. and globallyMonitoring needed
📊 Dividend YieldWhether dividends are being maintained at the level you expectMaintained normally

The share price of a particular stock can swing sharply depending on the clinical results or approval status of an individual new drug. A strategy that focuses on the growth potential of the sector as a whole over the long term is needed.

It is a reasonable choice for investing in the global pharmaceutical sector, which offers stable dividends and long-term growth potential. It works well as a way to strengthen the defensive power of a core portfolio.

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Disclaimer: This content is for informational purposes only and does not constitute investment advice. All investment responsibility lies with the investor.

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