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FMED ETF: What Is It? A Complete Guide to Returns, Expense Ratio, Holdings, and Alternative ETFs

Updated August 16, 2026 · First published August 16, 2026

The Fidelity Disruptive Medicine ETF, or FMED ETF, is an actively managed product that selects companies driving innovation in diagnostics, treatment, and healthcare services. It offers a reference framework for investors who care more about growth-theme prospects than dividends and want to review clinical results, regulatory changes, and related stock trends together.

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What Is the Fidelity Disruptive Medicine ETF?

The FMED ETF is a thematic, actively managed product that selects companies with the potential to change established approaches to medical diagnostics, treatment, and services. It seeks long-term capital growth, focusing on business areas tied to medical innovation such as gene therapy, robotic surgery, and digital health platforms.

It suits long-term investors who want exposure to the growth potential of the medical innovation theme and can tolerate the high volatility that comes with clinical and regulatory variables.

This is an ETF run by Fidelity using an active management approach.

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How Does the Fidelity Disruptive Medicine ETF Invest?

ItemDetails
BenchmarkMedical innovation theme
Management styleActive selection
Rebalancing frequencyAdjusted at the manager's discretion
Distribution frequencyNo distribution history
Expense ratio0.50%
ManagerFidelity

The fund uses bottom-up analysis to pick companies that could drive change in how medical diagnostics, treatment, and services are delivered. It may gain exposure to several paths of medical innovation, including gene therapy, robotic surgery, and digital health platforms, and position weights may vary depending on market conditions and the manager's assessment of company competitiveness.

  • Active selection concentrated in medical innovation
  • A thematic approach spanning diagnostics, treatment, and services
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Fidelity Disruptive Medicine ETF Size and Costs (AUM and Management Fee)

Assets under management (AUM) stand at $52.1M, and the expense ratio is 0.50% per year.

Because this is a thematic product that reflects Fidelity's management judgment, it is advisable to check not only the fee but also the stock selection criteria, changes in holdings, and trading conditions.

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Fidelity Disruptive Medicine ETF Performance and Trends

1-Year Price Performance
Dividend & Yield
1Y Return +19.9%
Next Ex-Dividend Date 12/20/2024
52-Week Price Range
$32
Low $23 High $33
vs. low +34.66% vs. high -4.14%

Returns on the medical innovation theme can be highly sensitive to clinical results, approval processes, research and development expectations, and the interest rate environment. The FMED ETF may lean toward specific growth areas rather than healthcare as a whole, so even when markets are stable, price swings may widen on company-specific news.

Fund flows into thematic medical products can be affected by expectations for new drug development, regulatory decisions, and shifts in risk appetite. Trading demand can change quickly in volatile markets, so it is worth checking the FMED ETF's bid-ask spread and trading conditions as well.

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Fidelity Disruptive Medicine ETF Pros and Cons

Its broad coverage of the medical innovation theme is a strength, but concentrated sector exposure and company-specific events can increase volatility.

💪 Key Strengths

Access to medical innovation
Lets you follow companies tied to changes in diagnostics, treatment, and services within a single theme.
Active selection
Rather than relying solely on an index's composition, the manager can reflect business changes and competitiveness through investment judgment.
Diversification across areas
May provide exposure to different innovation paths, such as gene therapy, medical devices, and digital health.

⚠️ Points to Watch

Thematic concentration risk
Even within healthcare, the fund leans toward innovation areas, so its performance may diverge from the broader market.
Clinical and regulatory variables
Trial results, approval decisions, and policy changes can significantly affect the value of related companies.
No distribution history
With no distribution history, it may not fit investors who prioritize regular cash flow.
Trading conditions check
Depending on market conditions, you should check the bid-ask spread and execution conditions.
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Fidelity Disruptive Medicine ETF Alternative and Related ETFs

Among the products shown in the comparison table, the GRNY ETF follows a large-cap selection strategy, the MAGS ETF concentrates on large technology stocks, and the ARKG ETF centers on the genomic innovation theme, so each has a different character. The XLSR ETF takes a sector rotation approach and the SSUS ETF uses a sector allocation method. When comparing them with the FMED ETF, you should look not only at fee levels and AUM but also at how direct the exposure to medical innovation is, whether the fund is actively managed, and what drives its volatility.

Peer Comparison ETFs
TickerNamePriceChangeAUMTotal Expense RatioDividend Yield1Y
MAGSMAGSRoundhill Magnificent Seven ETF$70.45-3.4%$5.8B0.30%1.39%+8.6%
GRNYGRNYFundstrat Granny Shots US Large Cap ETF$26.99-2.5%$4.4B0.75%0.13%+8.1%
ARKGARKGARK Genomic Revolution ETF$47.87-4.0%$2.0B0.75%-+56.6%
XLSRXLSRState Street US Sector Rotation ETF$66.21-1.4%$1.1B0.70%0.4%+9.9%
SSUSSSUSDay Hagan Smart Sector ETF$56.22-1.2%$610.8M0.76%0.45%+16.3%
Top Holdings
TickerNameWeightPriceChangeMarket CapP/EDividend Yield
LFSTLFSTLifeStance Health Group Inc0.04%$12.56+1.9%$4.8B96.6-
DHRDanaher Corp0.08%$229.75-1.8%$161.5B37.60.63%
BSXBoston Scientific Corp0.04%$46.01+3.4%$66.7B18.7-
ARGXArgen X SE ADR0.04%$875.76-1.6%$55.1B33.4-
COGTCOGTCogent Biosciences Inc0.04%$31.31-0.4%$5.4B--
ALNYAlnylam Pharmaceuticals Inc0.03%$227.28+1.0%$30.4B38.4-
ISRGIntuitive Surgical Inc0.03%$443.85+3.7%$156.8B53.7-
TXGTXG10x Genomics Inc0.03%$69.75-7.7%$9.1B--
VEEVVeeva Systems Inc0.03%$322.55+0.6%$52.2B53.1-
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Fidelity Disruptive Medicine ETF Investor Checkpoints

The medical innovation theme reflects both individual companies' research outcomes and regulatory decisions, so it is hard to treat it the same as a broad healthcare product. Before buying, review the product's management approach, distribution history, trading conditions, and currency exposure against your own goals and holding period.

CheckpointWhat to CheckCurrent Status
Fee burdenCheck the expense ratio and long-term holding costsNeeds checking
Management styleCheck active selection and changes in holdingsNeeds checking
Distribution historyWhether it fits a goal of regular cash flowNo distribution history
Trading conditionsCheck the bid-ask spread and executionNeeds checking

A structure that concentrates on a specific theme can be more sensitive to event-driven swings than a product covering healthcare as a whole. Clinical results, approval decisions, progress in competing technologies, the medical cost environment, and geopolitical variables can affect the outlook and market valuation of holdings, and investors who hold Korean won should also consider exchange rate movements.

The Fidelity Disruptive Medicine ETF can serve as a reference for investors who want to focus on the growth potential of medical innovation companies and understand the product's structure. However, given the lack of distribution history and the risk of thematic concentration, it is advisable to also review how its role differs from a broad healthcare product, its trading conditions, and how much volatility you can accept.

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Disclaimer: This content is for informational purposes only and does not constitute investment advice. All investment responsibility lies with the investor.

This article reflects information as of August 16, 2026.

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