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What Is the ASD ETF? — A Full Guide to Returns, Expense Ratio, Holdings, and Alternative ETFs

Updated August 20, 2026 · First published August 20, 2026

The Defiance Autism Spectrum Impact ETF, traded as ASD ETF, invests in publicly listed companies across the autism spectrum-related treatment, diagnostics, education, and care ecosystem. The outlook for ASD ETF can be influenced by clinical development, healthcare policy, demand for educational services, and individual company performance, making a theme-risk review essential.

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What Is the Defiance Autism Spectrum Impact ETF?

ASD ETF aims to track the total return of the BetaShares Autism Spectrum Impact Index. The index selects publicly listed companies in developed markets that provide products, services, or research for the autism spectrum and neurodiversity ecosystem, covering exposure to therapeutics, diagnostics, special education, and assistive technology businesses.

It is suited for investors who can evaluate the long-term investability of autism spectrum-related industries while accepting the regulatory and business-cycle volatility of healthcare, biotech, and educational services.

The fund is managed by Defiance ETFs as a passive (index-tracking) ETF.

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How to Invest in the Defiance Autism Spectrum Impact ETF

ItemDetails
Benchmark IndexBetaShares Autism Spectrum Impact Index
Management StylePassive index tracking
Rebalancing CyclePeriodic adjustments
Distribution CycleNo distribution history
Total Expense Ratio0.79%
Fund ManagerDefiance ETFs

ASD ETF, in principle, uses a replication method that holds index constituents at weights similar to the benchmark, and may use a representative sampling approach when required by execution conditions. Because the selected companies are filtered by the directness and materiality of their autism spectrum-related businesses, the inclusion criteria and performance drivers can differ from general healthcare products.

  • A theme-based framework covering the broader autism spectrum ecosystem
  • An index construction that incorporates therapeutics, diagnostics, special education, and assistive technology
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Defiance Autism Spectrum Impact ETF Size and Cost (AUM · Expense Ratio)

Assets under management (AUM) stand at $1.4M, and the total expense ratio is 0.79% per year.

Given the fund's status as a theme-concentrated ETF, investors should review trading conditions and the potential for market-price dislocation before transacting. The fee burden should be compared with similar theme products, using the total expense ratio as the key reference.

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Defiance Autism Spectrum Impact ETF Performance and Flows

1-Year Price Performance
Dividend & Yield
Dividend Yield 0.02%
Annual Dividend (TTM) $0.01
Next Ex-Dividend Date 6/24/2026
52-Week Price Range
$27
Low $25 High $29
vs. low +10.46% vs. high -4.77%

ASD ETF's performance can be sensitive to industry variables that compose the theme, such as clinical trials, regulatory reviews, healthcare service utilization, and education demand. Therefore, rather than judging the investment thesis solely on short-term price moves, it is necessary to examine how the index inclusion criteria and industry-specific business conditions affect the portfolio.

Capital flows into theme-based products can shift with healthcare and education policy, market risk appetite, and company-specific R&D news. Because ASD ETF is focused on a specific ecosystem, investors should review its concentration within the broader asset allocation when pairing it with broad market exposures.

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Defiance Autism Spectrum Impact ETF Strengths and Weaknesses

Theme clarity and index-based management are advantages, but sector concentration and volatility driven by regulatory and clinical variables are notable risks.

💪 Key Strengths

Theme Clarity
Focuses on business areas tied to the autism spectrum ecosystem, making the investment exposure easy to understand.
Index-Based Management
A passive approach following a pre-defined index reduces reliance on discretionary individual stock selection.
Ecosystem Coverage
Combines multiple business pillars, including therapeutics, diagnostics, education, and assistive technology.

⚠️ Points to Watch

Sector Concentration Risk
Regulatory changes or clinical results in healthcare, biotech, and related services can meaningfully affect performance.
Single-Stock Volatility
R&D progress, profitability shifts, and competitive dynamics can amplify share-price swings of constituent companies.
Trading Condition Review
Volume and the gap between market price and net asset value should be checked when buying or selling.
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Defiance Autism Spectrum Impact ETF Alternatives and Related Products

ASD ETF is a theme product with direct exposure to the autism spectrum ecosystem, and based on the data currently available, comparable listed funds tracking the same index or sharing the same investment objective are difficult to identify. Accordingly, no alternative tickers are presented with certainty. When investors separately review broader healthcare or education-related products, it is advisable to consult each product's prospectus to confirm how the inclusion criteria, sector concentration, fee burden, and trading conditions differ from ASD ETF.

Peer Comparison ETFs
TickerNamePriceChangeAUMTotal Expense RatioDividend Yield1Y
SMHSMHVanEck Semiconductor ETF$573.00+2.2%$72.4B0.35%0.19%+80.8%
GDXGDXVanEck Gold Miners ETF$95.48-0.5%$28.5B0.51%0.66%+38.8%
DRAMDRAMRoundhill Memory ETF$59.61+3.2%$24.6B0.65%--
CIBRCIBRFirst Trust NASDAQ Cybersecurity ETF$99.87-1.8%$16.6B0.58%0.39%+29.8%
IXNIXNiShares Global Tech ETF$143.64+0.8%$9.4B0.37%0.24%+43.5%
Top Holdings
TickerNameWeightPriceChangeMarket CapP/EDividend Yield
DFTXDFTXDefinium Therapeutics Inc0.05%$38.81+0.3%$5.2B--
LFSTLFSTLifeStance Health Group Inc0.03%$12.57-0.3%$4.8B96.7-
ACHCACHCAcadia Healthcare Company Inc0.03%$28.33-1.7%$2.6B--
ACADACADAcadia Pharmaceuticals Inc0.03%$27.29-0.6%$4.7B12.3-
MPLTMPLTMapLight Therapeutics Inc0.03%$10.92-3.5%$577.1M--
ABBVAbbvie Inc0.03%$263.96-0.0%$466.4B74.62.6%
BTSGBTSGBrightSpring Health Services Inc0.03%$56.78+0.3%$11.2B42.4-
RVTYRVTYRevvity Inc0.03%$143.45-2.2%$16.0B68.10.2%
BFAMBFAMBright Horizons Family Solutions Inc0.03%$65.67-2.1%$3.2B20.8-
JNJJohnson & Johnson0.03%$269.99-0.1%$650.6B31.31.99%

Investor Checklist for the Defiance Autism Spectrum Impact ETF

When evaluating ASD ETF, the social significance of the theme should be separated from investment performance, and the index inclusion criteria and sector concentration should be confirmed. Because healthcare and biotech-related companies can be affected by regulation, clinical development, and the commercialization process, the diversification benefits relative to other assets should also be considered.

CheckpointWhat to VerifyCurrent Status
Index Inclusion CriteriaConfirm the directness and materiality of autism spectrum-related businessesReview prospectus
Distribution PolicyCheck cash distribution history and policyNo distribution history
Trading ConditionsReview volume and bid-ask spread when buying or sellingConfirm before trading
Sector ConcentrationCheck concentration of exposure to healthcare, biotech, and educational servicesConcentrated exposure noted

This ETF is exposed to economic, regulatory, and technology variables affecting autism spectrum-related treatment, diagnostics, education, and care businesses. In biopharmaceuticals, clinical results and the approval process can drive business performance, while in healthcare services, policy and reimbursement conditions can have an impact. In addition, theme concentration can increase volatility relative to broad equity products.

The Defiance Autism Spectrum Impact ETF is a product that investors seeking index-based exposure to a specific neurodiversity ecosystem may consider. However, the absence of distribution history and theme concentration risk should be weighed together, and after reviewing fund size, trading conditions, fees, and the index methodology, the fund should be evaluated on a limited basis within the overall asset allocation.

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Disclaimer: This content is for informational purposes only and does not constitute investment advice. All investment responsibility lies with the investor.

This article reflects information as of August 20, 2026.

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