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What Does Sophia Genetics (SOPH) Do? — Stock Outlook, Earnings, Market Cap, Related Stocks, and Headquarters Overview

Updated June 18, 2026 · First published April 15, 2026

Sophia Genetics (SOPH) is a precision medicine company that operates the AI-powered genomic analysis platform Sophia DDM. As a small-cap healthcare growth stock, its share price, earnings, and market cap are highly sensitive to the expansion of its oncology-focused liquid biopsy business and its revenue growth trajectory.

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What kind of company is Sophia Genetics?

Sophia Genetics (SOPH) is a healthcare information services company that provides a cloud-based AI platform for genomic data analysis. Listed on the US Nasdaq, it has built a global network in the precision medicine and genomic analysis markets, centered on the Sophia DDM platform.

Its core business is a SaaS-style analysis platform that helps hospitals and research institutions standardize, analyze, and interpret genomic sequencing data. The company is expanding its operations into oncology-focused clinical genomic analysis, liquid biopsy applications, and biopharma collaboration services.

💰 How does Sophia Genetics make money?

Business SegmentRevenue MixDescription
Platform Analysis (Genomics)CoreSophia DDM analysis revenue from hospitals and research institutions
Liquid BiopsyKey Growth DriverAnalysis based on oncology-focused liquid biopsy applications
BiopharmaExpandingClinical trial support and decentralized data networks for pharmaceutical companies

The company has continued double-digit annual revenue growth recently. While platform analysis revenue provides a stable base, liquid biopsy applications are emerging as a key growth driver by pushing up contract pricing on new deals. The biopharma segment is adding diversification benefits through clinical trial support that leverages a global decentralized data network, and due to the subscription- and usage-based revenue structure, customer base expansion flows into gradual margin improvement. The company is still in the pre-profitability stage, with profitability improvement underway.

📐 Sophia Genetics market cap and company size

Market capitalization stands at $670.0M, and the company has 415 people employees.

It is a small-cap player positioned in the global genomic analysis software market. Rather than competing head-on with large diagnostics and sequencing companies, it occupies a differentiated position as a data analytics platform and is grouped with other precision medicine companies such as GH in liquid biopsy and NTRA in genetic testing. The company is currently in a stage focused on scaling top-line growth and transitioning to profitability.

📈 Sophia Genetics outlook and stock price trends

1-Year Price Performance
Analyst Consensus
1.0
Sell Hold Strong Buy
Target Price $10 +23.9% Current $8
52-Week Price Range
$8
Low $3 High $9
vs. low +153.87% vs. high -12.36%

Expanding demand for precision medicine and growth in the liquid biopsy market are the key medium- to long-term drivers. Genomic data accumulated on the Sophia DDM platform is improving AI analysis accuracy and reinforcing network effects, while the expansion of oncology-focused clinical applications and biopharma collaborations supports revenue diversification. In the short term, the pace of profitability inflection and new customer acquisition flows can act as stock price variables, and given the characteristics of a small-cap growth stock, the funding environment and changes in healthcare regulation and reimbursement policy remain potential sources of volatility.

  • Contract price increases driven by liquid biopsy application expansion
  • Improved AI analysis accuracy and network effects from accumulated platform data
  • Expansion of biopharma clinical collaborations

⚔️ Sophia Genetics core strengths and risks

The data network effects of its AI genomic analysis platform are a key strength, while the profitability inflection burden and small-cap growth stock volatility are the core risks.

💪 Core Strengths

Data Network Effects
Genomic data accumulated across numerous institutions improves AI analysis accuracy, creating a structure that is difficult for late entrants to replicate.
Platform Customer Lock-in
Analysis platforms integrated into hospital and research institution workflows carry high switching costs, translating into stable subscription revenue.
Business Diversification
Revenue streams are spread across genomics, liquid biopsy, and biopharma, lowering dependence on any single field.

⚠️ Core Risks

Profitability Inflection Burden
In the growth investment stage, any delay in reaching profitability could lead to multiple compression.
Small-Cap Volatility
A small market cap means the stock can react sharply to earnings or funding-related issues.
Regulation & Reimbursement Policy
Revenue is exposed to changes in healthcare diagnostic and testing reimbursement policies and data regulations.

🔄 Sophia Genetics competitors and related (beneficiary) stocks

Direct competitors grouped in the same precision medicine bucket include GH in liquid biopsy and oncology genomics, NTRA in genetic testing, and VCYT in genomic diagnostics. Related tickers grouped alongside the company include ILMN, which supplies sequencing instruments and consumables; TXG in single-cell and spatial genomics; and MSFT in cloud and AI infrastructure collaborations. Together, sequencing data generation and cloud-based analysis are operationally connected to Sophia Genetics' platform business.

Competitors
TickerCompanyPriceChangeMarket CapP/EPBRROEDividend Yield
GHGHGuardant Health Inc$157.47-1.0%$21.1B----
NTRANatera Inc$328.93+0.9%$47.4B-25.9-12.54%-
VCYTVCYTVeracyte Inc$40.87-2.8%$3.3B29.02.48.77%-
Related stocks (beneficiaries)
TickerCompanyPriceChangeMarket CapP/EPBRROEDividend Yield
ILMNIllumina Inc$206.47+2.6%$31.2B38.511.032.38%-
TXGTXG10x Genomics Inc$68.59+3.3%$8.9B-10.8-9.4%-
MSFTMicrosoft Corp$495.63+0.7%$3.68T27.68.334.04%0.79%

✅ Sophia Genetics investor checklist

Key points to review when considering Sophia Genetics as an investment. The sustainability of revenue growth and the pace of profitability inflection are the core short-term variables, and the progress of liquid biopsy expansion, new customer acquisition, and biopharma collaborations should also be monitored. | Checklist | What to Confirm | Current Status | |---|---|---| | Revenue Growth | Platform and liquid biopsy revenue growth trajectory | Expanding trend | | Liquid Biopsy Expansion | New contract pricing and expansion of oncology genomics applications | Growth phase | | Biopharma Collaborations | Order trends for pharmaceutical company clinical support | Recovery trend | | Profitability | Operating margin and capital efficiency trends | Inflection underway | As the company is in the growth investment stage, a delay in the profitability inflection could amplify share price volatility. Given the characteristics of a small-cap growth stock, it is sensitive to changes in the funding environment, and changes in healthcare reimbursement policy and data regulations can also act as short-term risk factors.

Sophia Genetics is a precision medicine small-cap growth stock whose key competitive advantage is the data network effects of its AI-based genomic analysis platform. Since the pace of profitability inflection and liquid biopsy expansion are the key variables to monitor, dollar-cost averaging and a long-term perspective are recommended.

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