USSTOCK.TODAY
Market Closed
Log in Sign up
Company overview

What Does OPKO Health (OPK) Do? – A Complete Guide to Stock Outlook, Earnings, Market Cap, Related Stocks, and Headquarters

Updated June 10, 2026 · First published April 14, 2026

OPKO Health (OPK) is a U.S. healthcare company that combines diagnostic testing with pharmaceuticals. Its revenue structure—anchored by specialty diagnostics through subsidiary Bio-Reference, the growth hormone NGENLA, and Rayaldee—along with earnings outlook and related-stock flows, serve as the key drivers of its share price.

Briefs · earnings · signals, first Subscribe

🏢 What kind of company is OPKO Health?

OPKO Health is a diversified U.S. healthcare company that operates both diagnostic testing services and pharmaceutical development. The company combines two pillars—diagnostics and novel therapeutics—to pursue testing revenue and product royalties simultaneously.

Its core businesses are specialty clinical diagnostics through its subsidiary Bio-Reference Health and a pharmaceutical product portfolio focused on chronic kidney disease and endocrinology. Within the Diagnostics & Research sector, OPKO occupies a position that addresses both testing and therapeutics.

💰 How does OPKO Health make money?

Business SegmentRevenue ShareDescription
Diagnostic ServicesCoreRevenue from Bio-Reference Health's specialty clinical tests (4Kscore, GenPath)
Pharmaceuticals & RoyaltiesKey Growth DriverProduct revenue and partner royalties from Rayaldee and NGENLA (somatrogon)
Research & OtherSupplementaryIncome from drug development and collaboration agreements

OPKO Health's revenue is structured with diagnostic testing services as its core, complemented by pharmaceuticals and royalties as the key growth driver. The diagnostics segment is being reorganized around specialty urology and oncology tests, reflecting the impact of the divestiture of certain clinical testing assets. The pharmaceutical segment is contributing to revenue diversification through the global rollout of the growth hormone NGENLA and prescription momentum for Rayaldee. The combined operation of testing volume and product royalties has the effect of lowering dependence on any single business.

📐 OPKO Health market cap and company size

Market capitalization stands at $1.2B, with 2,275 people employees.

OPKO Health belongs to the small- to mid-cap group within the Diagnostics & Research sector, positioned as a specialty player with a clear scale gap versus large clinical testing companies such as DGX and LH. Through its combined testing-and-pharmaceuticals model, the company pursues differentiated positioning relative to single-segment testing peers, managing capital allocation by balancing drug royalties and testing revenue.

📈 OPKO Health outlook and share price trends

1-Year Price Performance
Analyst Consensus
1.7
Sell Hold Strong Buy
Target Price $4 +180.8% Current $2
52-Week Price Range
$2
Low $1 High $2
vs. low +59.69% vs. high -9.83%

In the near term, clinical testing volume, changes in insurance reimbursement rates, and the post-divestiture revenue reshaping of certain diagnostic assets serve as key variables. Longer-term growth drivers include the global market expansion of growth hormone NGENLA, prescription-based growth of Rayaldee, and progress in the drug pipeline. However, intensifying competition in diagnostics, uncertainty in drug development, and changes in the reimbursement environment remain potential sources of volatility, requiring close monitoring of segment-level trends.

⚔️ OPKO Health key strengths and risks

A diversified structure combining diagnostics and pharmaceuticals is a strength, while drug development uncertainty and intensifying diagnostic competition are the main risks.

💪 Key Strengths

Business Diversification
Holds both diagnostic testing and pharmaceutical products, lowering dependence on any single business.
Specialty Diagnostic Assets
Maintains specialty testing lines such as the urology-focused 4Kscore and the oncology-focused GenPath.
Drug Royalties
Global expansion of growth hormone NGENLA is broadening the product and royalty revenue base.

⚠️ Key Risks

Drug Development Uncertainty
Pipeline development and regulatory approval processes are difficult to predict, which can amplify volatility.
Diagnostic Competition
Competition with large clinical testing companies may pressure testing prices and volumes.
Reimbursement Environment
Changes in insurance reimbursement rates and policy can directly affect diagnostic revenue.
OPKO Health competitors and related (thematic) stocks

Direct competitors in the same Diagnostics & Research sector include large clinical testing companies DGX and LH, molecular diagnostics player QGEN, and imaging diagnostics network RDNT. Related names grouped with OPKO Health's specialty testing themes include genomics and precision diagnostics company NTRA and liquid-biopsy-based oncology diagnostics company GH.

Competitors
TickerCompanyPriceChangeMarket CapP/EPBRROEDividend Yield
DGXDGXQuest Diagnostics Inc$237.89+1.2%$26.3B25.23.514.35%1.4%
LHLHLabcorp Holdings Inc$315.31+1.2%$25.6B26.13.011.74%0.94%
QGENQGENQiagen NV$41.88-1.5%$8.6B21.32.611.93%0.63%
RDNTRDNTRadnet Inc$75.49+0.0%$5.9B-5.4-2.08%-
Related stocks (beneficiaries)
TickerCompanyPriceChangeMarket CapP/EPBRROEDividend Yield
NTRANatera Inc$341.79+3.9%$49.3B-26.9-12.54%-
GHGHGuardant Health Inc$167.84+6.7%$22.5B----

✅ Investor checklist for OPKO Health

When evaluating OPKO Health, it is important to examine how diagnostic testing revenue and pharmaceuticals/royalties are each moving, as the balance between the two segments dictates earnings trends.

ChecklistWhat to VerifyCurrent Status
📈 Business MomentumTrends in diagnostic testing volume and product revenue diversificationUndergoing restructuring
💵 Financial HealthReview of profitability and cash flow metricsMonitoring required
🔬 Drug PipelineProgress in product expansion, including NGENLA and RayaldeeExpansion underway
⚔️ Competitive EnvironmentSpecialty positioning relative to large clinical testing companiesMonitoring required

Intensifying competition in diagnostics, changes in the insurance reimbursement environment, and drug development uncertainty are the main risks. If testing volume fluctuations and product revenue progress diverge, earnings visibility could weaken, making it essential to monitor segment-level trends side by side.

OPKO Health is a diversified healthcare company that combines specialty diagnostics with pharmaceuticals, with the balance between testing revenue and drug royalties at the core. A strategy of monitoring segment-level trends and pipeline progress, while approaching the stock through scaled buying and a long-term perspective, is recommended.

Briefs · earnings · signals, first Subscribe
Today's 5 AI picks, all free
Nothing hidden: past picks and how they did against the S&P 500.
See today's picks →